BDBM221244 US9303015, 18

SMILES COc1c(Oc2ccccc2)c(Cl)nc2ccc(cc12)C(O)(c1cncn1C)c1ccc(Cl)cc1

InChI Key InChIKey=SWUYOUYKNRCXJY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 221244   

TargetNuclear receptor ROR-gamma [258-518,Y502F](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221244(US9303015, 18)
Affinity DataIC50:  2.10E+3nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [258-518](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM221244(US9303015, 18)
Affinity DataKd:  1.70E+3nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent