BDBM22179 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2R)-2-methoxy-3-phenylpropyl]piperazine::GBR 12935 Analogue, (R)-9

SMILES CO[C@@H](CN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)Cc1ccccc1

InChI Key InChIKey=SPVLIWURVCWIKT-MUUNZHRXSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22179   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Taiwan University

LigandPNGBDBM22179(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2R)-2-...)
Affinity DataKi:  27nM ΔG°:  -9.59kcal/molepH: 7.4 T: 2°CAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Taiwan University

LigandPNGBDBM22179(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2R)-2-...)
Affinity DataKi:  250nMAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed