BDBM222083 4-(2-Furyl)-6-(4-nitrophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4e)

SMILES [O-][N+](=O)c1ccc(cc1)-c1cc(-c2ccco2)c(C#N)c(=O)[nH]1

InChI Key InChIKey=YEUOEHHTYFEKIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222083   

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Fayoum University

LigandPNGBDBM222083(4-(2-Furyl)-6-(4-nitrophenyl)-2-oxo-1,2-dihydropyr...)
Affinity DataIC50:  1.20E+3nMAssay Description:The ability of the tested compounds to inhibit both isozymes, COX-1 and COX-2 was measured using colorimetric COX (ovine) Inhibitor Screening Assay K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fayoum University

LigandPNGBDBM222083(4-(2-Furyl)-6-(4-nitrophenyl)-2-oxo-1,2-dihydropyr...)
Affinity DataIC50:  8.90E+3nMAssay Description:The ability of the tested compounds to inhibit both isozymes, COX-1 and COX-2 was measured using colorimetric COX (ovine) Inhibitor Screening Assay K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed