BDBM22211 1,2,4-oxadiazole based compound, 28::1-({4-[5-(4-ethoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)azetidine-3-carboxylic acid::US10676467, Compound TZ 35 100

SMILES CCOc1ccc(cc1)-c1nc(no1)-c1ccc(CN2CC(C2)C(O)=O)cc1

InChI Key InChIKey=IOIGVVYTXMGUFG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 22211   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22211(1,2,4-oxadiazole based compound, 28 | 1-({4-[5-(4-...)
Affinity DataIC50:  5.10nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22211(1,2,4-oxadiazole based compound, 28 | 1-({4-[5-(4-...)
Affinity DataIC50: >1.00E+3nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22211(1,2,4-oxadiazole based compound, 28 | 1-({4-[5-(4-...)
Affinity DataIC50: >1.00E+3nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22211(1,2,4-oxadiazole based compound, 28 | 1-({4-[5-(4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22211(1,2,4-oxadiazole based compound, 28 | 1-({4-[5-(4-...)
Affinity DataIC50:  8.53nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM22211(1,2,4-oxadiazole based compound, 28 | 1-({4-[5-(4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22211(1,2,4-oxadiazole based compound, 28 | 1-({4-[5-(4-...)
Affinity DataIC50:  48nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed