BDBM222636 US9315491, MTR-0404::US9801888, Compound MTR-0404
SMILES CSc1cnc(nc1N1CCOCC1)-c1ccc(NC(=O)Nc2ccc(cc2)S(C)(=O)=O)cc1
InChI Key InChIKey=IGGFJVBHFGTIRA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 222636
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 148nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 149nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair