BDBM222973 US9315518, 6-4

SMILES Cn1c2nc(ccc2n(CC2CC2(F)F)c1=O)C1=CC2CCC1CN2C(=O)c1ccon1

InChI Key InChIKey=WSMLYHXZMALWCQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222973   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222973(US9315518, 6-4)
Affinity DataEC50:  26.6nMAssay Description:The stimulation of [35S]-GTPγS binding is a common functional assay to monitor Gαi-coupled receptor in native and recombinant receptor memb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222973(US9315518, 6-4)
Affinity DataEC50:  29.0nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent