BDBM223054 US9321721, Example 2

SMILES COc1cccc(c1)C(=C\C(N)=O)\c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1

InChI Key InChIKey=VRSCFFWZVGDHSZ-CPNJWEJPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 223054   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM223054(US9321721, Example 2)
Affinity DataIC50:  945nMpH: 7.4Assay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent