BDBM223071 (E)-N'-(4'-Chlorobenzylidene)isonicotinohydrazide (3a)

SMILES Clc1ccc(\C=N\NC(=O)c2ccncc2)cc1

InChI Key InChIKey=AMDRLZATAWMLKJ-CXUHLZMHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 223071   

Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50:  1.67E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50:  1.79E+5nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate preincubated for 10 mins followed by substrate addition measured for 15 mins by spe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Quaid-I-Azam University

LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50:  670nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Quaid-I-Azam University

LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50:  1.08E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed