Found 25 hits for monomerid = 22319 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Solute carrier organic anion transporter family member 1B1 (OATP1B1)
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells |
Mol Pharmacol 83: 1257-67 (2013)
Article DOI: 10.1124/mol.112.084152 BindingDB Entry DOI: 10.7270/Q2TB18BP |
More data for this Ligand-Target Pair | |
Solute carrier organic anion transporter family member 1B3 (OATP1B3)
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells |
Mol Pharmacol 83: 1257-67 (2013)
Article DOI: 10.1124/mol.112.084152 BindingDB Entry DOI: 10.7270/Q2TB18BP |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein 5 (FABP5)
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 2.59E+3 | -7.74 | n/a | n/a | n/a | n/a | n/a | 8.2 | 30 |
Emory University
| Assay Description In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini... |
J Biol Chem 289: 14941-54 (2014)
Article DOI: 10.1074/jbc.M113.514646 BindingDB Entry DOI: 10.7270/Q21835CT |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein 5 (FABP5)(DSm)
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 5.01E+3 | -7.35 | n/a | n/a | n/a | n/a | n/a | 8.2 | 30 |
Emory University
| Assay Description In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini... |
J Biol Chem 289: 14941-54 (2014)
Article DOI: 10.1074/jbc.M113.514646 BindingDB Entry DOI: 10.7270/Q21835CT |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein 5 (FABP5)(NLSm)
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 9.37E+3 | -6.97 | n/a | n/a | n/a | n/a | n/a | 8.2 | 30 |
Emory University
| Assay Description In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini... |
J Biol Chem 289: 14941-54 (2014)
Article DOI: 10.1074/jbc.M113.514646 BindingDB Entry DOI: 10.7270/Q21835CT |
More data for this Ligand-Target Pair | |
TBXA2R
(MOUSE) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh
Curated by PDSP Ki Database
| |
Br J Pharmacol 79: 953-64 (1983)
Article DOI: 10.1111/j.1476-5381.1983.tb10541.x BindingDB Entry DOI: 10.7270/Q2SX6BPF |
More data for this Ligand-Target Pair | |
Cytosolic phospholipase A2 gamma
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd
Curated by ChEMBL
| Assay Description Concentration required to inhibit human Cytosolic phospholipase A2 |
Bioorg Med Chem Lett 11: 587-90 (2001)
Article DOI: 10.1016/s0960-894x(01)00003-8 BindingDB Entry DOI: 10.7270/Q2ST7P4R |
More data for this Ligand-Target Pair | |
Cytochrome P450 19A1
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago
Curated by ChEMBL
| Assay Description Inhibition of aromatase in human placental microsomes by radiometric method |
J Nat Prod 69: 700-3 (2006)
Article DOI: 10.1021/np050513p BindingDB Entry DOI: 10.7270/Q2J96647 |
More data for this Ligand-Target Pair | |
Calcium channel
(RAT) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University
Curated by ChEMBL
| Assay Description Inhibition of L-type calcium channel measured using whole-cell patch clamp in rat ventricular myocytes |
J Appl Toxicol 32: 858-66 (2012)
Article DOI: 10.1002/jat.2784 BindingDB Entry DOI: 10.7270/Q2D79D5C |
More data for this Ligand-Target Pair | |
Calcium channel
(RAT) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University
Curated by ChEMBL
| Assay Description Inhibition of L-type calcium channel measured using whole-cell patch clamp in rat ventricular myocytes |
J Appl Toxicol 32: 858-66 (2012)
Article DOI: 10.1002/jat.2784 BindingDB Entry DOI: 10.7270/Q2D79D5C |
More data for this Ligand-Target Pair | |
Fatty acid-binding protein 4 (FABP4)
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a |
University of Parma
Curated by ChEMBL
| Assay Description Binding affinity against Adipocyte lipid binding protein |
J Med Chem 45: 2469-83 (2002)
Article DOI: 10.1021/jm0200299 BindingDB Entry DOI: 10.7270/Q28916J7 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development LLC
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
J Med Chem 51: 7327-43 (2009)
Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8 |
More data for this Ligand-Target Pair | |
Sterol 14α-demethylase (CYP51)
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
ACT LLC
Curated by ChEMBL
| Assay Description Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay |
Drug Metab Dispos 35: 493-500 (2007)
Article DOI: 10.1124/dmd.106.013888 BindingDB Entry DOI: 10.7270/Q2DF6S2H |
More data for this Ligand-Target Pair | |
Vanilloid receptor
(Rattus norvegicus) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Council (CNR)
Curated by ChEMBL
| Assay Description Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins foll... |
J Med Chem 61: 8255-8281 (2018)
BindingDB Entry DOI: 10.7270/Q2222XFP |
More data for this Ligand-Target Pair | |
Vanilloid receptor
(Rattus norvegicus) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Research Council (CNR)
Curated by ChEMBL
| Assay Description Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins foll... |
J Med Chem 61: 8255-8281 (2018)
BindingDB Entry DOI: 10.7270/Q2222XFP |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2MG7SDK |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2MG7SDK |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2MG7SDK |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Coagulation factor VII/tissue factor
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Discovery Research
Curated by ChEMBL
| Assay Description Inhibition of amidolytic activity of human tissue factor/human factor 7a |
J Nat Prod 61: 1352-5 (1999)
Article DOI: 10.1021/np980117p BindingDB Entry DOI: 10.7270/Q2SF2VXF |
More data for this Ligand-Target Pair | |
Trypsin
(Sus scrofa) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Discovery Research
Curated by ChEMBL
| Assay Description Inhibition of pig pancreatic trypsin after 15 mins |
J Nat Prod 61: 1352-5 (1999)
Article DOI: 10.1021/np980117p BindingDB Entry DOI: 10.7270/Q2SF2VXF |
More data for this Ligand-Target Pair | |
Solute carrier organic anion transporter family member 1B1 (OATP1B1)
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 603 | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells |
Mol Pharmacol 83: 1257-67 (2013)
Article DOI: 10.1124/mol.112.084152 BindingDB Entry DOI: 10.7270/Q2TB18BP |
More data for this Ligand-Target Pair | |
Solute carrier organic anion transporter family member 1B3 (OATP1B3)
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells |
Mol Pharmacol 83: 1257-67 (2013)
Article DOI: 10.1124/mol.112.084152 BindingDB Entry DOI: 10.7270/Q2TB18BP |
More data for this Ligand-Target Pair | |
FABP5-ANS
(Mus musculus (Mouse)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 42.1 | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University School of Medicine
| Assay Description The method entails two steps [Lin et al., Biochemistry, 38:185-190]. In the first step, the Kd for association of FABP5 with the fluorescent lipid pr... |
J Biol Chem 289: 12748-58 (2014)
Article DOI: 10.1074/jbc.M114.559062 BindingDB Entry DOI: 10.7270/Q2P26X0Z |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB
Reactome pathway
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of PPAR-alpha (unknown origin) by SPA assay |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2K35XJ5 |
More data for this Ligand-Target Pair | |
Cyclooxygenase
(Homo sapiens (Human)) | BDBM22319
 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)Show InChI InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar
| Purchase
CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| n/a | n/a | n/a | 8.07E+3 | n/a | n/a | n/a | n/a | n/a |
Panjab University
| Assay Description Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ... |
Bioorg Chem 71: 201-210 (2017)
Article DOI: 10.1016/j.bioorg.2017.02.006 BindingDB Entry DOI: 10.7270/Q25T3JBP |
More data for this Ligand-Target Pair |  3D Structure (crystal) |