BDBM223197 2-Bromo-N-[3'-(1,1-dioxido-4-oxo-1,2,5-thiadiazolidin-2-yl)-4'-methyl[1,1'-biphenyl]-4-yl]-acetamide (5a)

SMILES Cc1ccc(cc1N1CC(=O)NS1(=O)=O)-c1ccc(NC(=O)CBr)cc1

InChI Key InChIKey=MPFQRXHRPDVJAC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 223197   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-322](Homo sapiens (Human))
University Of Missouri

LigandPNGBDBM223197(2-Bromo-N-[3'-(1,1-dioxido-4-oxo-1,2,5-thiadia...)
Affinity DataKi:  2.70E+4nM IC50:  5.40E+4nMpH: 7.0Assay Description:Assays for the reversible inhibition of PTP1B (72 nM) contained the test compound(2a, 2b, 5a, or 5b) in Bis-Tris (50 mM), NaCl (100 mM), EDTA (2 mM),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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