BDBM223269 2-(6-(Cyclopropylmethyl)(4-methylnaphthalen-1-yl)amino)-4-methoxynicotinoyl)cyclopropanecarboxylic acid::US20160326143, 44::US9657001, 44

SMILES COc1cc(ncc1C(=O)C1CC1C(O)=O)N(CC1CC1)c1ccc(C)c2ccccc12

InChI Key InChIKey=UEGPESZSLISMQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223269   

TargetLeukotriene C4 synthase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM223269(2-(6-(Cyclopropylmethyl)(4-methylnaphthalen-1-yl)a...)
Affinity DataIC50:  56nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM223269(2-(6-(Cyclopropylmethyl)(4-methylnaphthalen-1-yl)a...)
Affinity DataIC50:  56nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent