BDBM22358 1,3-Diarylprop-2-yn-1-one, 13o::3-(4-methanesulfonylphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-yn-1-one::CHEMBL194891

SMILES COc1cc(cc(OC)c1OC)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=QUSHLFKUHGFZFA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 22358   

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

LigandPNGBDBM22358(1,3-Diarylprop-2-yn-1-one, 13o | 3-(4-methanesulfo...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 37°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Human)
University of Alberta

LigandPNGBDBM22358(1,3-Diarylprop-2-yn-1-one, 13o | 3-(4-methanesulfo...)
Affinity DataIC50: >1.00E+5nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLipoxygenase(Potato)
University of Alberta

LigandPNGBDBM22358(1,3-Diarylprop-2-yn-1-one, 13o | 3-(4-methanesulfo...)
Affinity DataIC50:  7.00E+3nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM22358(1,3-Diarylprop-2-yn-1-one, 13o | 3-(4-methanesulfo...)
Affinity DataIC50:  7.00E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM22358(1,3-Diarylprop-2-yn-1-one, 13o | 3-(4-methanesulfo...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 2(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM22358(1,3-Diarylprop-2-yn-1-one, 13o | 3-(4-methanesulfo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

LigandPNGBDBM22358(1,3-Diarylprop-2-yn-1-one, 13o | 3-(4-methanesulfo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM22358(1,3-Diarylprop-2-yn-1-one, 13o | 3-(4-methanesulfo...)
Affinity DataIC50: >1.00E+4nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed