BDBM225040 US9321756, 2

SMILES Nc1nnc(o1)-c1ccc2[nH]cc(-c3cncc(n3)N3CCC(F)(F)CC3)c2c1

InChI Key InChIKey=VMTDEYJXDXLJNT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 225040   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM225040(US9321756, 2)
Affinity DataIC50:  1.94nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM225040(US9321756, 2)
Affinity DataIC50:  1.08nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM225040(US9321756, 2)
Affinity DataIC50:  2.26nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent