BDBM225177 US9328118, 94

SMILES CN1CCC[C@H]1C(=O)N1CCCC(COc2ccc(cc2C(F)(F)F)-c2nc(nc3n(C)ccc23)C#N)C1

InChI Key InChIKey=CWCKMOPJNSVSGX-LFABVHOISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 225177   

TargetCathepsin S(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM225177(US9328118, 94)
Affinity DataIC50:  3.60nMAssay Description:5 μL of a human cathepsin S enzyme (R&D1183-CY-010) was added to a 96-well plate so as to be 20 ng/well. Next, 10-fold dilution of the test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent