BDBM225217 US9328118, 149

SMILES CN1CCC[C@H]1C(=O)N1CCC(CC1)OCCOc1ncc(cc1C(F)(F)F)-c1nc(nc2n(C)ccc12)C#N

InChI Key InChIKey=DGWOFHACJHMULD-NRFANRHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 225217   

TargetCathepsin S(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM225217(US9328118, 149)
Affinity DataIC50:  2.70nMAssay Description:5 μL of a human cathepsin S enzyme (R&D1183-CY-010) was added to a 96-well plate so as to be 20 ng/well. Next, 10-fold dilution of the test comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent