BDBM22557 2-arylbenzimidazole derivative, 3::5-tert-butyl-2-{2-chloro-4-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}-1H-1,3-benzodiazole

SMILES CN1CCN(CCCOc2ccc(-c3nc4ccc(cc4[nH]3)C(C)(C)C)c(Cl)c2)CC1

InChI Key InChIKey=ZPKHJXYJHFUOGM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22557   

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22557(2-arylbenzimidazole derivative, 3 | 5-tert-butyl-2...)
Affinity DataKi:  93nM ΔG°:  -9.59kcal/molepH: 7.5 T: 25°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed