BDBM22558 2-arylbenzimidazole derivative, 4::4-{2-chloro-4-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}-3,5-diazatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),3,7,10,12-hexaene

SMILES CN1CCN(CCCOc2ccc(-c3nc4c(ccc5ccccc45)[nH]3)c(Cl)c2)CC1

InChI Key InChIKey=SKQKGGHCXLOMFJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22558   

TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22558(2-arylbenzimidazole derivative, 4 | 4-{2-chloro-4-...)
Affinity DataKi:  28nM ΔG°:  -10.3kcal/molepH: 7.5 T: 25°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed