BDBM22621 N-Me-pyrimidone deriv., 20::N-[(4-fluorophenyl)methyl]-5-hydroxy-2-[(2S,4S)-4-methanesulfonamido-1-methylpyrrolidin-2-yl]-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

SMILES CN1C[C@H](C[C@H]1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C)NS(C)(=O)=O

InChI Key InChIKey=KVQATFBBHKUIDY-KBPBESRZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22621   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Irbm-Mrl

LigandPNGBDBM22621(N-Me-pyrimidone deriv., 20 | N-[(4-fluorophenyl)me...)
Affinity DataIC50:  30nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed