BDBM227308 US9328106, 259

SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2ccc(cc2F)C(F)(F)F)c1[C@@H]1CC[C@@H](N)[C@@H](F)CO1

InChI Key InChIKey=FQPFSDUEXAZVDE-GUTXKFCHSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227308   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM227308(US9328106, 259)
Affinity DataKi:  0.0100nM ΔG°:  -15.0kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent