BDBM227479 US9334268, 11

SMILES CCOCc1nc2c(N)nc3cc(Br)ccc3c2n1CC(C)(C)OCCN

InChI Key InChIKey=RNJCSLXTDAQCMP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 227479   

TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM227479(US9334268, 11)
Affinity DataEC50:  130nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM227479(US9334268, 11)
Affinity DataEC50:  2.90E+3nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells, respectively, (Invivogen, San Diego, Calif., USA) transfected with a SEAP repo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent