BDBM227713 2-bromo-n-((2,6-dimethyl-4-oxo-1,4-dihydropyridin-3-yl)methyl)-5-(((trans)-4-(dimethylamino)cyclohexyl)(ethyl)amino)-4-methylthiophene-3-carboxamide::US9556157, 4
SMILES CCN([C@H]1CC[C@@H](CC1)N(C)C)c1sc(Br)c(C(=O)NCc2c(C)[nH]c(C)cc2=O)c1C
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 227713
Affinity DataIC50: 160nMpH: 8.0 T: 2°CAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair