BDBM227729 US9556181, 14::n-(6-fluoro-1h-indazol-5-yl)-3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES Fc1ccc(cc1)-c1n[nH]c2ncnc(Nc3cc4cn[nH]c4cc3F)c12

InChI Key InChIKey=OFPPUWTZHPDUHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227729   

TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227729(US9556181, 14 | n-(6-fluoro-1h-indazol-5-yl)-3-(4-...)
Affinity DataIC50:  12nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent