BDBM228021 US10047098, 47
SMILES COC[C@@H]1C[C@H]2C(=O)N(C)C(=N)N[C@]2(CO1)c1ccc(F)cc1F
InChI Key InChIKey=ZSTDDUYXLHRAMA-KNHMANMVSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 228021
Affinity DataKi: 5.72E+3nMpH: 5.0Assay Description:Reagents: Na+-Acetate pH 5.0; 1% Brij-35; Glycerol; Dimethyl Sulfoxide (DMSO); Recombinant human soluble BACE1 catalytic domain (>95% pure); APP Swed...More data for this Ligand-Target Pair
Affinity DataKi: 9.30E+3nMpH: 5.0Assay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair