BDBM228355 US10047093, 8-64::US10392392, Example 8-64::US10875864, EX. 8-64
SMILES OC[C@H]1CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(Cl)c3)c2n1
InChI Key InChIKey=VSCPITUJYKTOSN-SAZUREKKSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 228355
Affinity DataIC50: 68nMT: 2°CAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China).More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China). More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:hERG activity assays representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China). More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair