BDBM228520 US9340542, 9
SMILES Oc1ccc2C[C@]34CC[C@]5(C[C@]3(CCN(CC3CC3)C4)c2c1)NC(=O)NC5=O
InChI Key InChIKey=QCIIDNPIIDWWMQ-BHDDXSALSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 228520
Affinity DataKi: 148nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb...More data for this Ligand-Target Pair
Affinity DataKi: 676nM ΔG°: -8.41kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg mem...More data for this Ligand-Target Pair
Affinity DataEC50: 319nMpH: 7.4Assay Description:Functional [35S]GTPγS binding assays were conducted as follows. κ opioid receptor membrane solution was prepared by sequentially adding fin...More data for this Ligand-Target Pair
Affinity DataEC50: 309nMpH: 7.4Assay Description:[35S]GTPγS functional assays were conducted using freshly thawed p-receptor membranes prepared in-house from a cell line expressing recombinant ...More data for this Ligand-Target Pair