BDBM228611 US9345740, 8

SMILES CN[C@@H](C)C(=O)NC(Cc1ccc(cc1)C#CC(=O)NC1C[C@H](N(C1)C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C(=O)NC1CCCc2ccccc12)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)NC1CCCc2ccccc12

InChI Key InChIKey=SOUZAGJRYQSXAP-XXEPWGJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228611   

TargetE3 ubiquitin-protein ligase XIAP [125-356,C202A,C213G](Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM228611(US9345740, 8)
Affinity DataIC50:  4nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of His-BIR2-3 (125-356, C20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [241-356](Mus musculus (Mouse))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM228611(US9345740, 8)
Affinity DataIC50:  3nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of His-BIR3 (241-356, XIAP)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent