BDBM228631 US9345793, 12::US9744252, Example 12

SMILES OC(=O)C[C@H](NC(=O)[C@@H]1CCCN(C1)C(=O)CCC1CCNCC1)c1cncc(OCc2ccc(F)c(c2)C#N)c1

InChI Key InChIKey=ALPHCBAGUUJBBU-AMGIVPHBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228631   

TargetIntegrin alpha-IIb(Homo sapiens (Human))
Piramal Imaging

US Patent
LigandPNGBDBM228631(US9345793, 12 | US9744252, Example 12)
Affinity DataIC50:  8nMAssay Description:Purified human glycoprotein IIb/IIIa (20 mM Tris-HCl, 0.1 M NaCl, 0.1% Triton X-100, 1 mM CaCl2, 0.05% NaN3, 50% Glycerol, pH 7.4) was purchased from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Piramal Imaging

US Patent
LigandPNGBDBM228631(US9345793, 12 | US9744252, Example 12)
Affinity DataIC50:  8nMT: 2°CAssay Description:The GPIIb/IIIa receptor was immobilized 48 hours at least (100 μL per well, 48 to maximum 96 hours) on a 96-well solid plate (Immuno Plate MaxiSor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent