BDBM22986 18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2(7),3,5,12(17),13,15-heptaene::N-substituted tetracyclic indole::Tetracyclic indole derivative, 5

SMILES C(CCCn1c-2c(CCSc3ccccc-23)c2ccccc12)CCN1CCCCC1

InChI Key InChIKey=WXHMGIPWTRAKMK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22986   

TargetDNA ligase A(Mycobacterium tuberculosis)
India Central Drug Research Institute

LigandPNGBDBM22986(18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...)
Affinity DataIC50:  1.35E+4nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA ligase A(Mycobacterium tuberculosis)
India Central Drug Research Institute

LigandPNGBDBM22986(18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...)
Affinity DataIC50:  1.35E+4nMAssay Description:All assays have been carried out using procedures previously described by our group (Srivastava et al., 2005a; 2005b; 2007)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetDNA ligase 1(Homo sapiens (Human))
India Central Drug Research Institute

LigandPNGBDBM22986(18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...)
Affinity DataIC50:  2.12E+5nMpH: 8.0 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA ligase(Bacteriophage T4)
India Central Drug Research Institute

LigandPNGBDBM22986(18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...)
Affinity DataIC50:  2.04E+5nMpH: 7.6 T: 2°CAssay Description:The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed