BDBM230012 US9556135, 179

SMILES C[C@]1(CS(=O)(=O)[C@@](C)(F)C(N)=N1)c1cc(Nc2ncc(F)c3cc(cnc23)C#N)ccc1F

InChI Key InChIKey=ZFPMCSWQYHOKDP-LEWJYISDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 230012   

TargetCathepsin D(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM230012(US9556135, 179)
Affinity DataIC50: >4.44E+4nMpH: 3.5Assay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM230012(US9556135, 179)
Affinity DataIC50:  0.800nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent