BDBM230170 US9340500, I-014

SMILES Cc1c(cc(-c2ccccc2)n1CCCN1CCNCC1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=WQBRGUPVUSOQNH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230170   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM230170(US9340500, I-014)
Affinity DataKi:  355nM ΔG°:  -9.15kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent