BDBM230233 US9340500, I-077
SMILES CC(=O)N1CCC(CC1)c1cc(C(=O)Nc2cccc(c2)C(F)(F)F)c(C)n1CCCN1CCOCC1
InChI Key InChIKey=OYBGXOBKASKPNG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 230233
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 2.00E+3nM ΔG°: -8.08kcal/mole IC50: 4.70E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair