BDBM230248 US9340500, I-092
SMILES CNC(=O)CCn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F
InChI Key InChIKey=GFFFXMAEPLODCS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 230248
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 2.40E+3nM ΔG°: -7.97kcal/mole IC50: 6.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair