BDBM230363 US9340507, 25.2

SMILES CC[C@@H](C)n1cc(C(=O)NCc2nnc(C)o2)c(=O)c(-c2cccc(c2)C(F)F)c1C

InChI Key InChIKey=BCVSSHQBEJFMHP-GFCCVEGCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230363   

TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM230363(US9340507, 25.2)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5, containing 0.01% BSA. Test...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent