BDBM230971 US10188642, Example 97::US9334286, 97

SMILES COC1CN(C1)C(=O)c1ccc(Nc2cc3cc(ccc3cn2)-c2cnn(CC(C)(C)O)n2)c(OC)c1

InChI Key InChIKey=INSRKQJEWKCHOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 230971   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM230971(US10188642, Example 97 | US9334286, 97)
Affinity DataIC50:  9nMAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM230971(US10188642, Example 97 | US9334286, 97)
Affinity DataIC50:  9nMpH: 7.0 T: 2°CAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent