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BDBM23167 (2R)-2-amino-3-hydroxypropanoic acid::CHEMBL285123::D-Serine

SMILES: N[C@H](CO)C(O)=O

InChI Key: InChIKey=MTCFGRXMJLQNBG-UWTATZPHSA-N

Data: 1 KI  1 IC50

PDB links: 41 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23167   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proton-coupled amino acid transporter 1


(Homo sapiens (Human))
BDBM23167
PNG
((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Show SMILES N[C@H](CO)C(O)=O
Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
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Article
PubMed
2.20E+7n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting


Bioorg Med Chem 19: 6409-18 (2011)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.08.058
BindingDB Entry DOI: 10.7270/Q2NZ882D
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT)
BDBM23167
PNG
((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Show SMILES N[C@H](CO)C(O)=O
Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 670n/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound to inhibit [3H]-glycine binding to NMDA receptor


Bioorg Med Chem Lett 9: 1409-14 (1999)


Article DOI: 10.1016/s0960-894x(99)00194-8
BindingDB Entry DOI: 10.7270/Q2W0954Z
More data for this
Ligand-Target Pair