BDBM231675 N-(1,1-dioxothiolan-3-yl)-2-[(4-methylphenoxy)methyl]thiazole-4-carboxamide (4a)

SMILES Cc1ccc(OCc2nc(cs2)C(=O)NC2CCS(=O)(=O)C2)cc1

InChI Key InChIKey=VINDBUONEPJWMV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231675   

TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231675(N-(1,1-dioxothiolan-3-yl)-2-[(4-methylphenoxy)meth...)
Affinity DataIC50:  8.00E+4nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231675(N-(1,1-dioxothiolan-3-yl)-2-[(4-methylphenoxy)meth...)
Affinity DataIC50:  1.40E+3nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed