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BDBM23230 2-Oxosuccinic acid::2-oxobutanedioic acid::Oxaloacetate::Oxaloacetic acid::keto-Oxaloacetate

SMILES: OC(=O)CC(=O)C(O)=O

InChI Key: InChIKey=KHPXUQMNIQBQEV-UHFFFAOYSA-N

Data: 1 KI  1 Kd  1 ITC

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23230   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphoenolpyruvate carboxykinase (PEPCK H477R)


(Rattus norvegicus (Rat))
BDBM23230
PNG
(2-Oxosuccinic acid | 2-oxobutanedioic acid | Oxalo...)
Show SMILES OC(=O)CC(=O)C(O)=O
Show InChI InChI=1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9)
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KEGG
MMDB
PC cid
PC sid
UniChem

Patents

Article
PubMed
4.41E+5n/an/an/an/an/an/an/an/a



University of Waterloo



Assay Description
The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...


Biochemistry 56: 2106-2115 (2017)

More data for this
Ligand-Target Pair
Methyl-accepting chemotaxis protein (McpS)


(Pseudomonas putida (Arthrobacter siderocapsulatus))
BDBM23230
PNG
(2-Oxosuccinic acid | 2-oxobutanedioic acid | Oxalo...)
Show SMILES OC(=O)CC(=O)C(O)=O
Show InChI InChI=1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

KEGG
MMDB
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/a 2.39E+4n/an/an/an/a20



CSIC



Assay Description
Measurements were done on a VP-microcalorimeter (MicroCal, Amherst, MA).


J Biol Chem 285: 23126-36 (2010)

More data for this
Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 23230
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kcal/mole
-TΔS°
kcal/mole
ΔH°
kcal/mole
log KpHTemp
°C
Methyl-accepting chemotaxis protein (McpS)

(Pseudomonas putida (Arthrobacter siderocapsulatus))
BDBM23230
JPEG
(2-Oxosuccinic acid | 2-oxobutanedioic acid | Oxalo...)
GoogleScholar
CHEBI
KEGG
MMDB
PC cid
PC sid
-6.1923.8-30.34.62n/a20



CSIC





J Biol Chem 285: 23126-36 (2010)