BDBM232347 US9346794, 53

SMILES Cc1c(-c2cccc(c2)C(F)(F)F)c(=O)c(cn1C1CCOCC1)C(=O)NCc1ccc(cc1)S(C)(=O)=NC#N

InChI Key InChIKey=JTWKXKKUCPGUDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 232347   

TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM232347(US9346794, 53)
Affinity DataIC50:  2.30nMpH: 7.5 T: 2°CAssay Description:The following buffers were used: Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent