BDBM232443 US9346795, 251

SMILES CCCCc1c(c(nn1-c1ccc(Oc2cccc(Cl)c2)cc1)C(=O)OCC)-c1ccc(cc1C(=O)N1CCc2ccccc2C1)C(=O)NS(=O)(=O)c1ccc2c(Cl)ccc(Br)c2c1

InChI Key InChIKey=HHTKSQRKQAZSQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 232443   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM232443(US9346795, 251)
Affinity DataIC50:  50nMT: 2°CAssay Description:The assays were performed in black flat-bottom 384-well plates. The final assay volume was 55 μl prepared from additions of Biotin-Bcl-xL (Bcl-x...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM232443(US9346795, 251)
Affinity DataIC50:  20nMT: 2°CAssay Description:The assays were performed in black flat-bottom 384-well plates. The final assay volume was 50 μl prepared from additions of Gst-Bcl-2 (Bcl-2: GE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent