BindingDB logo
myBDB logout

BDBM233054 Thiolactomycin (TLM, 1)

SMILES: C\C(C=C)=C/C1(C)SC(=O)C(C)=C1O

InChI Key: InChIKey=SYQNUQSGEWNWKV-VOTSOKGWSA-N

Data: 1 IC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233054   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
β-Ketoacyl-acyl carrier protein (ACP) synthase III (FabH)


(Mycobacterium tuberculosis)
BDBM233054
PNG
(Thiolactomycin (TLM, 1))
Show SMILES C\C(C=C)=C/C1(C)SC(=O)C(C)=C1O
Show InChI InChI=1S/C11H14O2S/c1-5-7(2)6-11(4)9(12)8(3)10(13)14-11/h5-6,12H,1H2,2-4H3/b7-6+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 7.49E+4n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (...


J Enzyme Inhib Med Chem 25: 240-9 (2010)

More data for this
Ligand-Target Pair