BDBM22988 (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide::AEA::ANANDAMIDE::Arachidonoyl ethanolamide::Arachidonoyl ethanolamide (AEA)::Arachidonoylethanolamide (AEA)::Arachidonylethanolamide::CHEMBL15848::[14C]Anandamide::[3H]Anandamide
SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
InChI Key InChIKey=LGEQQWMQCRIYKG-DOFZRALJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 90 hits for monomerid = 22988
Affinity DataKi: 11nM ΔG°: -11.0kcal/molepH: 7.4 T: 30°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]CP-55,940 binding to Cannabinoid receptor 1 in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity towards cannabinoid receptor using [3H]CP-55940 as radioligand in rat brain membraneMore data for this Ligand-Target Pair
TargetCB1 cannabinoid receptor-interacting protein 1(Duck leech)
State University of New York At Old Westbury
Curated by PDSP Ki Database
State University of New York At Old Westbury
Curated by PDSP Ki Database
TargetCannabinoid receptor 1(Medicinal leech)
State University of New York At Old Westbury
Curated by PDSP Ki Database
State University of New York At Old Westbury
Curated by PDSP Ki Database
Affinity DataKi: 39nMAssay Description:In vitro binding affinity was determined against rat brain Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 39.2nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity to CB1R (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity for human cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Ability to displace [3H]HU-243 binding to cannabinoid receptor in synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the presence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H...More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in human HEK293 cells in presence of 100 nM PMSFMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Binding affinity to human recombinant CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]CP55-940 from human recombinant CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]CP55-940 from human recombinant CB1 receptor in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Binding affinity to human recombinant CB1 receptor expressed in african green monkey COS cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Binding affinity for cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes in presence of FAAH inhibitor PMSF by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Binding affinity for the cannabinoid receptor in the presence of phenylmethanesulfonyl fluoride (PMSF) was determined in rat fore brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Displacement of [3H]-CP-55,940 from Cannabinoid receptor 1 of rat forebrain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Tested for binding affinity to Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Binding affinity towards cloned human Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Binding affinity to CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in Wistar rat brain incubated for 60 mins by radioactive filter binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Binding affinity for Cannabinoid receptor 1 in presence of phenylmethylsulfonyl fluoride (PMSF)More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Binding affinity to human CB1 receptor in presence of serine protease inhibitor PMSFMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:The compound was tested for Ki value against rat whole brain P2 membrane preparation in presence of enzyme inhibitor PMSF.More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Binding affinity of the compound towards Cannabinoid receptor 1 in rat forebrain membranes using [3H]-CP-55,940 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 111nMAssay Description:The following fluorescent ligand displacement assays at 24 °C were used to further confirm and/or determine if the cytosolic lipidic ligand "chaperon...More data for this Ligand-Target Pair
Affinity DataKi: 132nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellar membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor expressed in HEK293 cell membranes in absence of FAAH inhibitor PMSF by radioligand binding ass...More data for this Ligand-Target Pair
Affinity DataKi: 168nM ΔG°: -9.39kcal/molepH: 7.4 T: 30°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Universidad Complutense
Curated by ChEMBL
Universidad Complutense
Curated by ChEMBL
Affinity DataKi: 169nMAssay Description:Binding affinity to vanilloid VR1 receptor using [3H]resiniferatoxin ([3H]-RTX) in rat spinal cord membranesMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Displacement of [3H]CP55-940 from human recombinant CB2 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Displacement of [3H]CP55-940 from human recombinant CB2 receptor in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Binding affinity to human recombinant CB2 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 282nMAssay Description:Binding affinity towards cannabinoid receptor using [3H]SR-141,716A as radioligand in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 285nMAssay Description:Binding affinity to CB1 cannabinoid receptor using [3H]WIN-55212-2 in rat cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with W6 48(357)A mutant in Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with W5 43(280)A mutant Cannabinoid receptor 1 at 5...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with F3.36 (201)A mutant Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Ability of the compound to displace [3H]-CP-55,940 from the membranes prepared from HEK cell line with wild type Cannabinoid receptor 1More data for this Ligand-Target Pair