BDBM233328 US9346814, Ref Cmpd No 9

SMILES O=C(CNC(=O)c1ccnc2ccccc12)N1CCCC1C#N

InChI Key InChIKey=MTHMMXFBHKGAAI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 233328   

TargetProlyl endopeptidase FAP(Mus musculus (Mouse))
Universiteit Antwerp

US Patent
LigandPNGBDBM233328(US9346814, Ref Cmpd No 9)
Affinity DataIC50: >1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Universiteit Antwerp

US Patent
LigandPNGBDBM233328(US9346814, Ref Cmpd No 9)
Affinity DataIC50: >1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universiteit Antwerp

US Patent
LigandPNGBDBM233328(US9346814, Ref Cmpd No 9)
Affinity DataIC50:  2.24E+4nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Universiteit Antwerp

US Patent
LigandPNGBDBM233328(US9346814, Ref Cmpd No 9)
Affinity DataIC50:  2.40E+3nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Universiteit Antwerp

US Patent
LigandPNGBDBM233328(US9346814, Ref Cmpd No 9)
Affinity DataIC50: >1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent