BDBM23336 1-{5-methyl-12-oxo-11,17-diazatetracyclo[11.3.1.0^{2,11}.0^{3,8}]heptadeca-3(8),4,6-trien-17-yl}-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione::Tetracyclic aza-amide, 5b

SMILES COc1cc(cc(OC)c1OC)C(=O)C(=O)N1C2CCCC1C(=O)N1CCc3ccc(C)cc3C21

InChI Key InChIKey=QSQVKKFKZQGQFF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23336   

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23336(1-{5-methyl-12-oxo-11,17-diazatetracyclo[11.3.1.0^...)
Affinity DataKi:  85nM ΔG°:  -9.32kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed