BDBM234456 US10004738, 9::US9353084, 9

SMILES Cn1cc(Br)nc1C(=O)Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)[C@@](C)(F)CC1(F)F

InChI Key InChIKey=HOESHHMMCCAKCR-DLBZAZTESA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234456   

TargetBeta-secretase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM234456(US10004738, 9 | US9353084, 9)
Affinity DataKi:  100nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM234456(US10004738, 9 | US9353084, 9)
Affinity DataKi:  100nMpH: 4.5Assay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent