BDBM234475 US10004738, 28::US9353084, 28

SMILES C[C@@]1(F)CC(F)(F)[C@](C)(N=C1N)c1cc(NC(=O)c2ccc(cn2)C(F)(F)F)ccc1F

InChI Key InChIKey=ZAMLOFZOUSOLCR-QZTJIDSGSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234475   

TargetBeta-secretase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM234475(US10004738, 28 | US9353084, 28)
Affinity DataKi:  170nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM234475(US10004738, 28 | US9353084, 28)
Affinity DataKi:  170nMpH: 4.5Assay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent