BDBM234483 US10004738, 36::US9353084, 36

SMILES C[C@@]1(F)CC(F)(F)[C@](C)(N=C1N)c1cc(NC(=O)c2nccs2)ccc1F

InChI Key InChIKey=PZMYIHWMYVSDEE-HZPDHXFCSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234483   

TargetBeta-secretase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM234483(US10004738, 36 | US9353084, 36)
Affinity DataKi:  390nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM234483(US10004738, 36 | US9353084, 36)
Affinity DataKi:  390nMpH: 4.5Assay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent