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BDBM234590 US9353093, 12

SMILES: Cc1ccccc1NC(=O)Nc1ccc(cc1)-c1cc2ccccc2n1C(N)=O

InChI Key: InChIKey=YRGIFNDOEPYLFQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234590   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor subunit B (PDGFB)


(Homo sapiens (Human))
BDBM234590
PNG
(US9353093, 12)
Show SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-c1cc2ccccc2n1C(N)=O
Show InChI InChI=1S/C23H20N4O2/c1-15-6-2-4-8-19(15)26-23(29)25-18-12-10-16(11-13-18)21-14-17-7-3-5-9-20(17)27(21)22(24)28/h2-14H,1H3,(H2,24,28)(H2,25,26,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 118n/an/an/an/an/an/a



Allergan, Inc.

US Patent


Assay Description
Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...


US Patent US9353093 (2016)


BindingDB Entry DOI: 10.7270/Q2BZ64ZV
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM234590
PNG
(US9353093, 12)
Show SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-c1cc2ccccc2n1C(N)=O
Show InChI InChI=1S/C23H20N4O2/c1-15-6-2-4-8-19(15)26-23(29)25-18-12-10-16(11-13-18)21-14-17-7-3-5-9-20(17)27(21)22(24)28/h2-14H,1H3,(H2,24,28)(H2,25,26,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 174n/an/an/an/an/an/a



Allergan, Inc.

US Patent


Assay Description
Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...


US Patent US9353093 (2016)


BindingDB Entry DOI: 10.7270/Q2BZ64ZV
More data for this
Ligand-Target Pair