BDBM234867 US9353116, Fig. 16, Compound 6

SMILES COc1cc2ncnc(Nc3cccc(NS(=O)(=O)c4cccs4)c3)c2cc1OC

InChI Key InChIKey=QXUWPMGTRJTVHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234867   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234867(US9353116, Fig. 16, Compound 6)
Affinity DataIC50:  57.7nMAssay Description:In vitro kinase assays using LRRK WT and LRRK G2019S.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM234867(US9353116, Fig. 16, Compound 6)
Affinity DataIC50:  329nMAssay Description:In vitro kinase assays using LRRK WT and LRRK G2019S.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent