BDBM234974 4-(1-(2-chloro-6-(trifluoromethyl)benzyl)-1H-pyrazolo[3,4-c]pyridin-3-yl)-3-fluorobenzoic acid::US9556168, 1A

SMILES COC(=O)c1ccc(-c2nn(Cc3c(Cl)cccc3C(F)(F)F)c3cnccc23)c(F)c1

InChI Key InChIKey=QDFPMRONZBLFHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234974   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM234974(4-(1-(2-chloro-6-(trifluoromethyl)benzyl)-1H-pyraz...)
Affinity DataIC50:  142nMpH: 7.0Assay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent