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BDBM235199 US9365558, 22

InChI string: InChI=1/C29H29F7N2O6S/c1-43-18-7-5-17(6-8-18)21-16-27(29(34,35)36,37-25(39)24(21)26(40)38-45(41,42)20-10-11-20)22-12-9-19(15-23(22)30)44-14-4-2-3-13-28(31,32)33/h5-9,12,15,20H,2-4,10-11,13-14,16H2,1H3,(H,37,39)(H,38,40)/t27-/s2

SMILES: COc1ccc(cc1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F

InChI Key: InChIKey=YDLANPMJPOHYAN-XUESUEPENA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235199   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM235199
PNG
(US9365558, 22)
Show SMILES COc1ccc(cc1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C1)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F
Show InChI InChI=1/C29H29F7N2O6S/c1-43-18-7-5-17(6-8-18)21-16-27(29(34,35)36,37-25(39)24(21)26(40)38-45(41,42)20-10-11-20)22-12-9-19(15-23(22)30)44-14-4-2-3-13-28(31,32)33/h5-9,12,15,20H,2-4,10-11,13-14,16H2,1H3,(H,37,39)(H,38,40)/t27-/s2
UniProtKB/SwissProt

antibodypedia
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US Patent
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...


US Patent US9365558 (2016)

More data for this
Ligand-Target Pair